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Original Article

The Effect of Oestradiol on the Arterial Diameter in Mice, as Studied by Angiography

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Pages 363-365 | Received 18 Apr 1972, Published online: 09 Jul 2009
 

Abstract

Ten spayed female mice received a subcutaneous injection of 1 μg of ocstradiol-benzoate. Whole body angiography was performed on the oestrogen-treated and untreated controls. The diameters of the arteries supplying the head, neck, fore limbs, pelvis and posterior limbs were measured with an optical micrometer. The arteries of the head, neck and fore limbs in the oestrogen-treated group were smaller in diameter, while the diameter of the internal iliac artery (hypogastric trunk) was larger when compared with controls. The results are discussed in relation to recent findings in humans.

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