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Abstract
Summary.
The author first gives a short historical account of the treatment of the purulent otogenous meningitis, pointing out the complete change brought about by modern chemotherapy. He then gives an account of his own researches and states that the so-called blood-liquor bar transmits preparations belonging to the sulfanilamid group, specially in cases of meningitis. The author advances a blood-liquor quotient, the relation between the concentration of sulfapyridine in blood and liquor, which may be important for judging the prognosis in cases of otogenous meningitis. If the meninges show inflammatory conditions the blood-liquor quotient decreases; during recovery it increases and is relatively high in sound patients. At last it is stated that the conditions for indicating operation in cases of otogenous complications have changed so that it is nowadays permissible to wait longer than before.