On Quantitative Cytochemical Changes in Spiral Ganglion Cells After Acoustic Trauma

Abstract

During the last 50 years a large number of investigations have been made in the form of studies of the structural changes in the cells of the spiral ganglion as a result of acoustic trauma. The aim of the present investigation has been to make a study of the chemical composition of these cells with reference to certain important groups of matter, namely ribonucleic acid (RNA), proteins, and lipids. Quantitative methods now exist for the analysis of single nerve cells in a cyto scala. It is therefore possible to study the processes which constitute the cytochemical background of the structural changes in the cell and which display the cell's physiological changes.