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Abstract
The DNA content in a biopsy material of bronchogenic carcinomata was measured by a microspectro—photometric technique. The average content of DNA was considerably elevated as compared with the normal broncial epithelial nuclei. The number of polyploid tumour—cell nuclei was 10 times as large in squamous—cell carcinoma and adenocarcinoma as in oat—cell carcinoma. The formation of the polyploid nuclei and their role in malignancy are discussed.