Vasodilatation In The Nasal Mucosa Of The Cat And The Effects Of Parasympatholytic And β-Adrenergic Blocking Agents

Abstract

Stimulation of the vidian nerve in cats within a certain range of intensities evokes an increased venous flow from the nose and a decreased nasal patency. These effects are assumed to be due to vasodilatation, which is highly resistant to the parasympatholytic agent, piperidino-ethyl-diphenylacetamide (Hoechst 9980). The vasodilatation was not significantly changed at stimulation after the combination of Hoechst 9980 and a β-adrenergic blocking agent, propranolol. Possible vasodilator mechanisms are discussed.