Lithium Treatment of Meniere's Disease Results of a Double-blind Cross-over Trial

J. Thomsen ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

P. Bech ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

A. Geisler ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

S. Prytz ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

O. J. Rafaelsen ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

P. Vendsborg ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

K. Zilstorff ENT Department, Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark

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Abstract

21 patients with Meniere's disease participated in a double-blind, cross-over trial, with 6 months' lithium treatment and 6 months' placebo treatment. Even if the results were not completely unequivocal, no difference was found between lithium and placebo treatment. The results might imply that both other medical as well as surgical treatment of Meniere's disease exert a pure placebo effect; so far no controlled investigation has been published, establishing the value of surgical treatment of Meniere's disease.

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Lithium Treatment of Meniere's Disease Results of a Double-blind Cross-over Trial

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Lithium Treatment of Meniere's Disease Results of a Double-blind Cross-over Trial

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