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Acta Oto-Laryngologica Volume 116, 1996 - Issue 6
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Original Article

Localization of Cu/Zn-SOD and Mn-SOD in the Rat Cochlea

Kyle E. Rarey Departments of Anatomy & Cell Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA; Departments of Otolaryngology, College of Medicine, University of Florida, Gainesville, FL, 32610, USACorrespondence[email protected]
&
Xiaofei Yao Departments of Anatomy & Cell Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA
Pages 833-835 | Received 02 Oct 1995, Accepted 13 Mar 1996, Published online: 08 Jul 2009
 
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Abstract

Rarey KE, Yao X. Localization of Cu/Zn-SOD and Mn-SOD in the rat cochlea. Acta Otolaryngol (Stockh) 1996; 116: 833-835.

Distributions of the copper/zinc-superoxide dismutase (Cu/Zn-SOD) and the manganese superoxide dismutase (Mn-SOD) in the rat cochlea were studied by immunohistochemistry with specific polyclonal antibodies to Mn-SOD and Cu/Zn-SOD. Coexpression of Mn-SOD and Cu/Zn-SOD was observed in the cochlear tissues with differing immunoactivity intensities. the presence of Cu/Zn- and Mn-SOD implies the existence of a defense system against free oxygen radical (FOR) injury in cochlear tissues.

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