Reliability of nerve function assessments for people with peripheral neuropathy

Abstract

Examining degenerative sensory and reflexive activity among people with peripheral neuropathy (PN) is important for clinical examinations and understanding relevant neural impairments. However, other than the test of presynaptic inhibition, the reliability of other related tests is largely unknown. The purpose of this project was to examine the test–retest reliability of lower extremity sensory and reflexive measures in people with PN. Twelve participants (8 women, 4 men, age = 72.5 ± 9.2 years) diagnosed with PN were assessed on two occasions at least 7 d apart. Plantar sensitivity, H-reflex and active and passive ankle proprioception (AAP and PAP) were tested. Paired student's t-test and Intraclass correlation coefficients (ICC) were used for statistical analysis. Significant difference was observed in AAP at 0º position (p = 0.04). No other significant differences were observed. Moderate to high reliability was observed at measures of Plantar sensitivity (0.92), peak to peak H (0.71) and M (0.84) waves, latency between H and M (0.78), H-Index (0.85), AAP (0.62) and PAP index (0.60). Low reliability was observed of other parameters. The measures of H_max, M_max, latency, H-Index, plantar sensitivity and AAP & PAP indices of proprioception tests can be measured reliably for further study in this population.

KEYWORDS:

• reliability
• peripheral neuropathy
• ankle proprioception
• tactile sensation
• H-Reflex
• H-index

Acknowledgements

Shuqi Z. was responsible for study design, data collection and analysis, interpretation of data and manuscript. Matthew H. was responsible for participant recruitment, data collection and revising the manuscript. Li L. was responsible for the study design, analysis and revising the manuscript.

Declaration of Interest

The authors report no conflict of interest. The authors alone are responsible for the content and writing of this paper.