![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Synaptosomes were found to contain endogenous substrates in sufficient amount to support physiological ion equilibrium and to maintain the resting oxygen consumption rate. Exogenous substrates were required only in functional states which brought about an increase of oxygen consumption: depolarization or uncoupling. The addition of glucose, pyruvate or glutamate increased oxygen consumption only in the presence of a stimulating agent. Succinate increased oxygen consumption even in the resting phase but proved to be incapable of supplying energy for synaptosomal ion transport processes.