Abstract
There is a clear indication for the use of psychotropic analgesic nitrous oxide in conjunction with psychotherapy in the treatment of patients where excessive anxiety is a major component of the symptomatology and especially in patients unresponsive to traditional psychotherapy. Although only a relatively small sample was studied over a short time period, the beneficial results in the majority of patients were clear. Patient acceptability was high. The treatment is extremely safe and produced accelerated behavioral change with stability and integration maintained after 4 weeks. However, the administration of psychotropic analgesic nitrous oxide is extremely technique sensitive and therefore requires supervised on-hands training with the correct fail-safe equipment to maximise the benefit of the therapy for both physician and patient.