Crossed cerebro-cerebellar diaschisis in a patient with melas with aphasia but without hemiparesis

N.I.L.J. Bohnen Departments of Neurology and Nuclear Medicine, Mayo Clinic, Rochester, MN, 55905

M. Beran-koehn Departments of Neurology and Nuclear Medicine, Mayo Clinic, Rochester, MN, 55905

B. Mullan Departments of Neurology and Nuclear Medicine, Mayo Clinic, Rochester, MN, 55905

J. R. Fulgham Departments of Neurology and Nuclear Medicine, Mayo Clinic, Rochester, MN, 55905

Abstract

We describe a 25 year old woman diagnosed with MELAS during an acute stroke-like episode. Global aphasia, migraine-like headaches and hemi-anopsia were her main clinical features. MR imaging revealed extensive cortical and subcortical left hemispheric signal abnormalities. [Tc-99m]ECD SPECT scanning revealed crossed cerebrocerebellar diaschisis. Aphasia in the absence of gross hemi-paresis can be related to cross-cerebellar diaschisis in MELAS.

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Crossed cerebro-cerebellar diaschisis in a patient with melas with aphasia but without hemiparesis

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Crossed cerebro-cerebellar diaschisis in a patient with melas with aphasia but without hemiparesis

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