Standardization of the Bromsulphalein Test with respect to Body Composition

Abstract

Brohult, J. Standardization of the Bromsulphalein Test with respect to Body Composition. Scand. J. clin. Lab. Invest. 19 67–71,1967. A procedure is described for calculating the dose of BSP so that the quantity administered gives an initial level with a narrower spread than when the dose is given per kg body weight. The procedure involves dosage in relation to the fat-free soft tissue, estimated by an anthropometric method. The two types of calculation have been compared in healthy subjects as well as in alcoholics with various degrees of liver disease. Both groups showed a significantly narrower spread of the initial values when the dose was calculated from the estimated weight of the fat-free soft tissue. The usefulness of this in clinical practice is discussed.