Renal Function in Unilateral, Parenchymatous Renal Disease in Normotensive and Hypertensive Patients

Abstract

In 32 patients with unilateral, parenchymatous renal disorders (16 with hypertension), filtration fraction of affected and normal kidneys, and the ratio between filtration fractions of affected and normal kidneys, were greatest in hypertensive patients. The excretion fraction of sodium and the osmotic clearance per unit glomerular filtrate were greater and the urinary concentration of inulin was least in affected kidneys without difference between normotensive and hypertensive patients. It is suggested that hypertension affects diseased and normal kidneys in the same way.

Key Words:

• Hypertension
• renal disease
• unilateral
• renal function