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Original Article

Thyroidal Iodine and Proteins in Autoimmune Thyroiditis

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Pages 263-268 | Received 31 Oct 1969, Accepted 24 Feb 1970, Published online: 08 Jul 2009
 

Abstract

The iodine content of thyroid tissue from patients with autoimmune thyroid itis was determined in 10 cases. The concentration was usually below 60 μg/g of tissue wet weight and the total content below 4000 μg. The thyroidal proteins were studied in 8 patients. In four thyroglobulin formed from 25 to 52 per cent of the thyroid proteins. Two patients who had the lowest iodine content were hypothyroid. There is a correlation between the decrease in thyroglobulin, the decrease in iodine content, and the appearance of clinical hypothyroidism.

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