Cobalamin binding proteins in human seminal plasma

Abstract

Transcobalamin (TC) and haptocorrin (HC) are present in normal seminal plasma in substance concentrations ten- to twenty-fold that in blood. The results are given in range and (median). The substance concentration of seminal plasma TC is 3.6-21.9 (8.4) nmoir¹ and of seminal plasma HC 1.4-8.6 (3.0) nmol l⁻¹. Compared to normals the substance concentration of TC is significantly lowered in post-vasectomy seminal plasma 2.2-2.9 (5.3) nmol l⁻¹. The Stokes radius and the isoelectric points of seminal plasma TC are identical to TC in blood.

Key Words:

• cobalamin-binding proteins
• haptocorrin
• transcobalamin
• seminal plasma