Scintigraphic Localization of Intermittent Gastrointestinal Haemorrhage with Indium-111-Labelled Platelets

K. Gjerløff Schmidt Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

J. Wæver Rasmussen Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

O. Grove Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

P. E. Rørbæk Madsen Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

R. Bargum Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

D. Andersen Dept. of Nuclear Medicine, Dept. of Medical Gastroenterology, and Dept. of Surgical Gastroenterology, Odense University Hospital, Odense, and Dept. of General Surgery, Svendborg Hospital, Svendborg, Denmark

Abstract

Because of the central role of blood platelets in haemostasis, ¹¹¹In-labelled platelets might be supposed to participate in the haemostatic process and give rise to scintigraphic hot spots at the bleeding sites in cases of intermittent gastrointestinal haemorrhage. Three patients with intermittent gastrointestinal haemorrhage are described in whom focal tracer accumulations after injection of autologous ¹¹¹In-labelled platelets indicated the presence of transient gastrointestinal haemorrhage. Repeatedly performed scintigraphy after injection of ¹¹¹In-labelled platelets may prove to be a useful tool for the localization of intermittent gastrointestinal haemorrhage.

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Scintigraphic Localization of Intermittent Gastrointestinal Haemorrhage with Indium-111-Labelled Platelets

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Scintigraphic Localization of Intermittent Gastrointestinal Haemorrhage with Indium-111-Labelled Platelets

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