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Scandinavian Journal of Gastroenterology Volume 22, 1987 - Issue 3
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Original Article

Characteristics of Reflux Gastritis

S. Niemelä Dept. of Internal Medicine, Dept. of Pathology, and Dept. of Clinical Chemistry, University Central Hospital of Oulu, Oulu, Finland
,
T. Karttunen Dept. of Internal Medicine, Dept. of Pathology, and Dept. of Clinical Chemistry, University Central Hospital of Oulu, Oulu, Finland
,
J. Heikkilä Dept. of Internal Medicine, Dept. of Pathology, and Dept. of Clinical Chemistry, University Central Hospital of Oulu, Oulu, Finland
&
J. Lehtola Dept. of Internal Medicine, Dept. of Pathology, and Dept. of Clinical Chemistry, University Central Hospital of Oulu, Oulu, Finland
Pages 349-354 | Received 22 Aug 1986, Accepted 10 Nov 1986, Published online: 08 Jul 2009
 
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Abstract

The amount of postprandial duodenogastric bile reflux was correlated with detailed histologic findings in the stomachs of 107 patients with dyspepsia. The reflux was associated with infiltration of mononuclear leukocytes, neutrophilic granulocytes, and eosinophilic granulocytes and with foveolar hyperplasia in the gastric mucosa. No significant association with intestinal metaplasia emerged. Our results suggest that postprandial duodenogastric bile reflux is characterized by superficial inflammatory changes in the gastric mucosa.

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