Comparison of Indirect Diagnostic Methods for Hypolactasia

H. Arola Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

T. Koivula Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

H. Jokela Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

M. Jauhiainen Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

O. Keyriläinen Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

T. Ahola Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

A. Uusitalo Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

M. Isokoski Dept. of Public Health, University of Tampere, Tampere, Finland; Central Laboratory, Dept. of Medicine, Tampere, Finland; Laboratory of Clinical Physiology, University Central Hospital of Tampere, Tampere, Finland; Central Laboratory, University Central Hospital of Kuopio, Kuopio, Finland

show all

Abstract

The aim of this study was to continue our previously published work and to compare the different indirect diagnostic methods for hypolactasia with the lactase to sucrase ratio obtained by jejunal biopsy. The following tests were performed in 63 adult patients: the breath hydrogen test, the lactose tolerance test with ethanol (serum galactose measurement after oral lactose load with ethanol), the urinary lactose tolerance test (urinary galactose measurement after oral lactose load with ethanol), and the strip test (like the former but using a special test strip for urinary galactose). Specificities of all these tests were good (96-98%). The 3-h breath hydrogen test was less sensitive (69%) than the other methods (81-94%). The strip test is recommended for the general practitioner for the diagnosis of this common cause of abdominal complaints.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Comparison of Indirect Diagnostic Methods for Hypolactasia

Information for

Open access

Opportunities

Help and information

Comparison of Indirect Diagnostic Methods for Hypolactasia

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature