Influence of Food-Intake during a Fixed Period on Hydrocortisone-Induced Relapse of Acetic Acid Ulcers in Rats

Abstract

We studied the influence of food-intake during a fixed period on hydrocortisone-induced relapse of acetic acid ulcers in rats. The ulcer index, the defective area of the ulcerated region and the exposure index for the ulcer floor in the food-intake-time limited group markedly increased as compared to those in the control group. The index for the regenerated mucosa decreased in the food-intake-time limited group. Thus, hydrocortisone-induced relapsed ulcers were markedly increased by limiting the food-intake-time.

Key Words:

• Gastric ulcer
• hydrocortisone
• rats
• relapsed ulcer