Necrotizing myositis and septic shock caused by Haemophilus influenzae type f in a previously healthy man diagnosed with an IgG3 and a mannose-binding lectin deficiency

Abstract

An increased incidence of infections by Haemophilus influenzae type f (Hif) has recently been suggested, but such infections have mainly been regarded as opportunistic. We present here a dramatic case of Hif necrotizing myositis and septic shock. A subsequently diagnosed IgG3 and mannose-binding lectin deficiency possibly contributed to the severe outcome.

Keywords::

• Haemophilus influenzae
• myositis
• IgG3 deficiency
• MBL deficiency

Acknowledgements

This work was supported by grants from the Alfred Österlund Foundation, the Anna and Edwin Berger Foundation, the Capio Research Foundation, the Greta and Johan Kock Foundation, the Gyllenstierna Krapperup Foundation, the Physiographical Society in Lund, the Cancer Foundation at the University Hospital in Malmö, and Skåne County Council's Research and Development Foundation.

Declaration of interest: None of the authors of this manuscript have any competing interests, financial or other.