Raltegravir-induced DRESS syndrome

Abstract

DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is a life-threatening adverse drug reaction. Raltegravir is an integrase inhibitor used in HIV-1 infection. We report on a patient who developed a DRESS syndrome under raltegravir treatment, which was identified as a probable case of DRESS on the basis of Kardaun and Naranjo scores. The presented case is the first description of a proven raltegravir-induced DRESS syndrome.

Keywords::

• DRESS syndrome
• HIV
• raltegravir
• integrase inhibitors
• pharmacology

Declaration of interest: Dr Mir has acted as a paid consultant for Roche.