Increased Prevalence of Cytomegalovirus Antibodies in Homosexual Men with Syphilis: Relation to Sexual Behaviour

Peter Kryger Department of Rubella, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Treponematoses, Statens Seruminstitut, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Jan Gerstoft Department of Rubella, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Treponematoses, Statens Seruminstitut, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Nils S. Pedersen Department of Rubella, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Treponematoses, Statens Seruminstitut, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Jens O. Nielsen Department of Rubella, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Treponematoses, Statens Seruminstitut, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Abstract

Serum samples from 146 homosexual males, 40 heterosexual males and 51 females with at least one episode of syphilis were tested for the presence of IgG and IgM antibodies against Cytomegalovirus (CMV IgG and CMV IgM). 100 blood donors served as a control group. CMV IgG was present in 95% of homosexual men compared with 68% of heterosexual men (p < 0.001) and 73% of females (p < 0.001) with past or present syphilis. CMV IgM was found in 43-68% of the venereal patients and with the highest percentage in homosexual men. Only 7% of blood donors had CMV IgM. It is concluded that CMV infection may be regarded as a venereal disease.

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Increased Prevalence of Cytomegalovirus Antibodies in Homosexual Men with Syphilis: Relation to Sexual Behaviour

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Increased Prevalence of Cytomegalovirus Antibodies in Homosexual Men with Syphilis: Relation to Sexual Behaviour

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