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CaseReport Article

Nosocomial Cerebral Aspergillosis: A Report of 3 Cases

, , , , &
Pages 317-319 | Received 25 Oct 1995, Accepted 12 Mar 1996, Published online: 08 Jul 2009
 

Abstract

Cerebral aspergillosis carries a mortality rate close to 100%, especially in immunocompromised patients. We describe 3 patients who contracted cerebral aspergillosis after neurosurgery, 2 of whom survived after exhaustive surgical treatment and medical treatment with high doses of amphotericin B (once liposomal), 5-fluorocytosine and itraconazole. We review the few non-fatal cases of cerebral aspergillosis reported. We consider that surgical excision must be complete and repeated if necessary, always in combination with medical treatment.

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