Alloplastic Replacement of the Partially Resected Urinary Bladder in Dogs

Abstract

The upper half of the urinary bladder in two dogs was replaced by a gelatin sponge graft. Both animals died of urinary leakage.

Lyophilized human dura was used as a graft for bladder regeneration after partial cystectomy in 8 dogs. Three dogs died of urinary leakage, while the others survived in good general condition. The animals were sacrificed between 2 weeks and 4 months after the operation. At autopsy, the graft was found to be replaced by scar tissue, and the bladder top was contracted in all the dogs. There was no stone formation. If contraction can be avoided, lyophilized human dura should be acceptable for bladder reconstruction in man.