Proteinuria After Human Renal Transplantation: II. A Functional Identification of Two Types of Rejection Crisis

Abstract

In human renal allotransplantation two functionally different types of rejection crisis were detected. Type I was characterised by an early, abrupt decrease in urine output and an initially reduced fractional sodium and low molecular weight (LMW) protein excretion. Type II was characterised by a later and more insidious onset without oliguria, with no reduction of fractional sodium excretion and with an increased LMW protein excretion.