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The American Journal of Drug and Alcohol Abuse
Encompassing All Addictive Disorders
Volume 2, 1975 - Issue 2
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Original Article

Evoked Potential Changes During Ethanol Withdrawal in Rats

Henri Begleiter Department of Psychiatry Downstate Medical Center, State University of New York Brooklyn, New York, 11203
&
Marc Coltrera Department of Psychiatry Downstate Medical Center, State University of New York Brooklyn, New York, 11203
Pages 263-268 | Published online: 07 Jul 2009
 
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Abstract

We have recently observed an increase in central nervous system excitability during intoxication and alcohol withdrawal in alcoholics. Our present results demonstrate a similar phenomenon in rats. The hyper-excitability caused by ethanol withdrawal is still present subsequent to the overt behavioral symptoms of withdrawal.

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