Failure of Prolactin Infusion to Elicit Adrenal Androgen Secretion

L. N. Parker Department of Medicine, Division of Endocrinology, VA Medical Center, Long Beach, CA, 90822

V. Atienza Department of Medicine, Division of Endocrinology, Torrance, CA, 90509

O. C. Haggans Department of Medicine, Division of Veterinary Clinic, UCLA-Harbor Medical Center, Torrance, CA, 90509

W. D. Odell Department of Medicine, University of Utah, 50 North Medical Drive, Salt Lake City, UT, 84132

Abstract

In order to test the theory that prolactin (Prl) regulates adrenal androgen (AA) secretion, large doses of bovine Prl were acutely infused into castrated dogs, and similar studies were performed with ovine Prl in castrated sheep. Prl with low-dose ACTH stimulation did not cause AA secretion beyond that which occurred following ACTH stimulation alone, and Prl alone did not stimulate AA secretion in vivo.

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Failure of Prolactin Infusion to Elicit Adrenal Androgen Secretion

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Failure of Prolactin Infusion to Elicit Adrenal Androgen Secretion

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