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Archives of Andrology
Journal of Reproductive Systems
Volume 7, 1981 - Issue 1
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Original Article

Effect of Zinc Administration on Plasma Testosterone, Dihydrotestosterone, and Sperm Count

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Pages 69-73 | Received 23 Jun 1980, Published online: 09 Jul 2009
 

Abstract

The effects of zinc therapy on plasma testosterone (T), dihydrotestosterone (DHT), and sperm count were studied in 37 patients with idiopathic infertility of more than five years duration. In the first group (T < 4.8 ng/ml; 22 patients), T and DHT rose significantly after oral administration of zinc, as did the sperm count. Nine wives became pregnant, six within 3 months and three within 2 months of a second trial. In the second group (T > 4.8 ng/ml; 15 patients), T and sperm count were unaffected by zinc, while DHT increased significantly. There was no conception observed. The rationale of this treatment and the significance of the results are discussed.

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