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Archives of Andrology
Journal of Reproductive Systems
Volume 10, 1983 - Issue 1
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Original Article

Sleep Deprivation Reduces Circulating Androgens in Healthy Men

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Pages 33-37 | Received 01 Aug 1982, Published online: 09 Jul 2009
 

Abstract

The acute effect of sleep deprivation on the pituitary-testis axis was evaluated in 13 healthy men. To study such association, the circulating levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), Androstenedione (A), Testosterone (T), Dihydro-testosterone (DHT) and Estradiol (E2) were measured along with Cortisol (C) before and after sleep deprivation. Morning (8:00 AM) venous blood samples were obtained prior and after a continuous restless period of 24 hr and the values were analyzed by the paired Student's t test. There was a significant and parallel decrease of each androgen and E2 but not of FSH, L.H. PRL, or C, associated with the acute sleep deprivation.

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