Cellular Immunolocalization of Inhibinlike Peptide in Human Benign Prostatic Hyperplasia

Abstract

Immunoperoxidase staining method and specific antisera against highly purified inhibinlike material (ILM) from human seminal plasma were utilized to localize immunoreactive ILM in benign hyperplastic prostate (BPH) in human. Immunoreactive ILM was strictly localized to glands of hyperplastic nodules. The concentration of ILM was more in epithelial cells lining the healthy lobule than in those undergoing atrophy.

Key Words:

• Inhibin
• Benign prostatic hyperplasia (BPH)
• Immunoperoxidase.