High Seminal Sialic Acid Concentrations in Patients with Severe Teratozoospermia

D. Du Toit Centre for Fertility Studies, Department of Urology, University of Pretoria, and the HF Venvoerd Hospital, Private Bag X169, Pretoria, 0001, South Africa

M. S. Bornman Centre for Fertility Studies, Department of Urology, University of Pretoria, and the HF Venvoerd Hospital, Private Bag X169, Pretoria, 0001, South Africa

M. P. Van Der Merwe Centre for Fertility Studies, Department of Urology, University of Pretoria, and the HF Venvoerd Hospital, Private Bag X169, Pretoria, 0001, South Africa

D. J. Du Plessis Centre for Fertility Studies, Department of Urology, University of Pretoria, and the HF Venvoerd Hospital, Private Bag X169, Pretoria, 0001, South Africa

Abstract

Seminal plasma and sperm-bound sialic acid (SA) concentrations were evaluated in patients with severe teratozoospermia (< 5% morphologically normal sperm) and correlated with values of a control group with >20% morphologically normal sperm. The SA concentrations both in seminal plasma and on sperm were significantly higher in teratozoospermia, but the ratio of sperm-bound SA to seminal plasma SA remained virtually the same. The causes and consequences of high SA in these patients need further study.

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High Seminal Sialic Acid Concentrations in Patients with Severe Teratozoospermia

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High Seminal Sialic Acid Concentrations in Patients with Severe Teratozoospermia

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