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Archives of Andrology
Journal of Reproductive Systems
Volume 29, 1992 - Issue 2
78
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Original Article

Number and DNA Content of Hypertrophic Spermatogonia in Normal and Cryptorchid Human Testes

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Pages 157-162 | Published online: 09 Jul 2009
 

Abstract

The number and the DNA content of hypertrophic spermatogonia were studied in normal and cryptor-chid testes. The number of hypertrophic spermatogonia in cryptorchid testes is higher than in control testes at the same age. This finding suggests alterations in the spermatogonia of cryptorchid males. The results show a polyploid DNA content in more than 80% of hypertrophic spermatogonia in both normal and cryptorchid testes. There were hypertrophic spermatogonia with a DNA content between 2c and 4c (0.5%) and between 4c and 8c (9%). These spermatogonia might be cells in the S phase of the cell cycle.

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