Hypoosmotic Swelling: Evaluation of Sperm Tails Using Strict Criteria in Cases of Globozoospermia

Abstract

The semen from two men with globozoospermia was evaluated for hypoosmotic swelling changes and morphologic evaluation of the tail using strict criteria. No abnormalities were noted. Globozoospermia is due to a genetic defect that results in the absence of acrosomal structures. The acrosomal vesicle in the Golgi region does not develop in close contact to the nucleus, which results in the formation of globe-shape heads. Although some semen parameters were abnormal in both cases, they were different types, suggesting no association with round-headed sperm.

Key Words:

• Globozoospermia
• Round-headed sperm
• HOS Test
• Acrosome
• Strict morphology.