Mesenchymal orbital tumors

Abstract

Thirty-two mesenchymal orbital tumors diagnosed and treated between 1963–1993 were reviewed. The patient population included seven cases with fibrocytic, twelve cases with osseous, three cases with cartilaginous and ten cases with lipocytic tumors. The diagnosis was made by histopathologic examination in every case. Fibrocytic tumors included two cases of fibroma, one case of fibrous histiocytoma and four cases of fibrosarcoma. Osseous tumors comprised nine osteomas, one osteosarcoma, one fibrous dysplasia and one ossifying fibroma. Of the three lesions classified as cartilaginous tumors two were chondromas and one was primary chondrosarcoma. Lipocytic tumors consisted of five cases of liposarcoma, three cases of lipoma, one case of myxoma and one case of dermolipoma. Follow-up period ranged from 12 to 57 (mean: 24) months. Benign mesenchymal tumors were treated with local excision and orbitotomy. Sarcomatous mesenchymal tumors were treated with wide local excision accompanied by radiotherapy and chemotherapy in some cases. Total exenteration was performed in two cases with fibrosarcomas because of massive proptosis and a painful blind eye. Five cases (two liposarcomas, one fibrosarcoma, one osteosarcoma and one chondrosarcoma) deceased at 4.2 to 25.4 months from the initial diagnosis. The cause of death was systemic metastasis in one of the cases with liposarcoma and local recurrence and aggressive tumor growth in the remaining four cases.

Key Words:

• Chondroma
• chondrosarcoma
• dermolipoma
• fibrous dysplasia
• fibrous histiocytoma
• lipoma; liposarcoma
• orbit
• myxoma
• ossifying fibroma
• osteoma
• osteosarcoma