Impact of Studies of the Drosophila norpA Mutation on Understanding Phototransduction

Abstract

Abstract: Studies of the norpA mutation have significantly contributed to understanding the molecular and biochemical basis of phototransduction in Drosophila. Historical milestones in the study of the norpA mutation are reviewed and a contemporary model of the role of the NORPA protein in vision is presented. Questions awaiting further investigations are discussed.

Keywords::

• melanopsin
• phospholipase C
• photoreceptor
• rhabdomere
• signalplex
• vision

Declaration of interest: The author reports no conflict of interest. The author alone is responsible for the content and writing of the paper.