Abstract
The sorption of 5-fluorouracil from aqueous solutions onto poly(methyl methacrylate) was investigated. Linear sorption isotherms were obtained and no crystallinity of the nanoparticles after sorption was detectable by X-ray analysis indicating a partitioning of the drug into the polymer particles forming a solid solution. Standard enthalpy, standard entropy and standard free energy of sorption were -36.9 kJ mol−1 -85.0 J mol−1 K−1 and -12.0 kJ mol−1, respectively.