1,693
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Reusable heat-sensitive phantom for precise estimation of thermal profile in hyperthermia application

, , &
Pages 66-74 | Received 04 Jul 2013, Accepted 09 Oct 2013, Published online: 28 Nov 2013
 

Abstract

Purpose: The emergence of thermal modalities has promoted the use of heat-sensitive phantoms for calibration, measurement, and verification purposes. However, development of durable phantoms with high precision ability to represent the temperature distribution remains a challenge. This study aims to introduce a reusable phantom that provides an accurate assessment of the heated region in various thermal modalities. Materials and methods: The phantom contains a thermochromic dye that is transparent blue at room temperature and becomes colourless after exceeding a threshold temperature. In order to determine the threshold temperature of the phantom, spectrophotometry analysis was performed. The various thermal (specific heat, thermal conductivity, melting point and latent heat of melting) and acoustic (sound speed, attenuation) properties of this phantom were measured and compared with those of the reference phantom without dye. The application of this phantom for radio-frequency and magnetic resonance guided focused ultrasound modalities was also examined. Results: The spectrophotometry analysis showed a threshold temperature of 50 ± 3 °C for this phantom. The results also demonstrated a 6 °C difference between the onset and ending temperatures of the discolouration process. Moreover, the starting temperature of colouration during cooling was found to be 4 °C lower than the ending temperature of discolouration. The sound speed, attenuation, specific heat, thermal conductivity and melting point of the heat-sensitive phantom were statistically equal to those of the reference phantom; however, the latent heat, and onset temperature of the melting of the heat-sensitive phantom were decreased by addition of the dye. Conclusions: The developed phantom is applicable for accurate evaluation of temperature variations in various thermal modalities.

Acknowledgements

The authors wish to thank Thermographic Measurements for providing the thermochromic dye. We would also like to extend our gratitude to Mohammed Rafiq and Maheza Irni from University of Technology Malaysia (UTM) for their support in performing acoustic characterisation tests, Mohammad Mehrali for evaluation of thermal properties, and Yus Hafizul from University of Malaya Medical Centre for conducting the MRgFUS experiments.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.