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Abstract
Two patients with Parkinson's disease (PD) treated successfully with subthalamic nucleus deep brain stimulation (STN-DBS) for 3–4 years are reported, who demonstrated a persistent improvement following removal of STN-DBS for late infection. Possible hypotheses are discussed – whether a microlesioning effect or a disease-modifying effect of STN-DBS, though neither adequately explain this phenomenon.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.