Increased growth rate of a WHO grade I ganglioglioma during pregnancy

Abstract

We report the case of a 32-year-old woman with a left frontal ganglioglioma (WHO grade I). Quantitative analysis based on three dimensional magnetic resonance images revealed a threefold increase of growth rate during pregnancy as compared to pre-pregnancy, causing neurological deterioration and leading to prompt surgical treatment 3 months after delivery.

Keywords::

• ganglioglioma
• low-grade glioma
• pregnancy
• growth rate

Acknowledgements

We thank Dr Catherine Miquel for reviewing the histology and Dr Michèle Felce for providing the histochemistry analysis.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.