Creatine Kinase BB Release into Cerebrospinal Fluid After Lateral Ventricle Cannulation

Abstract

Creatine kinase (CK) and creatine kinase BB isoenzyme (CK-BB) activities were measured in ventricular CSF obtained by lateral ventricle cannulation in patients suspected of normal pressure hydrocephalus. Lateral ventricle cannulation resulted in highly and variably elevated CK and CK-BB levels. The results emphasise the interference of these CK and CK-BB elevations in studies on the prognostic value of CSF CK and CK-BB levels in head trauma patients with respect to outcome.

Key Words:

• Cerebrospinal fluid
• creatine kinase isoenzyme
• head injury
• hydrocephalus