Expression of epidermal growth factor receptor in human glioblastoma multiforme

T. J. D. Pigott Departments of Neurosurgery, The University of Nottingham Medical School, Nottingham, NG7 2 UH, UK

D. K. Robson Departments of Pathology, The University of Nottingham Medical School, Nottingham, NG7 2 UH, UK

J. Palmer Departments of Pathology, The University of Nottingham Medical School, Nottingham, NG7 2 UH, UK

L. M. Ward Departments of Pathology, The University of Nottingham Medical School, Nottingham, NG7 2 UH, UK

Abstract

The expression of epidermal growth factor receptor was determined in a series of 88 patients with glioblastoma multiforme using a monoclonal antibody to the receptor. Positive staining was seen in 17 patients but this did not have prognostic significance when compared with known clinical prognostic factors using a computer model. The significance of receptor expression in these tumours is discussed.

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Expression of epidermal growth factor receptor in human glioblastoma multiforme

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Expression of epidermal growth factor receptor in human glioblastoma multiforme

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