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Original Article

Influence of Blue Light-filtering Intraocular Lenses on Retinal Nerve Fiber Layer Measurements by Spectral-domain Optical Coherence Tomography

, , , , &
Pages 937-942 | Received 30 Jul 2010, Accepted 11 Jun 2011, Published online: 27 Sep 2011
 

Abstract

Purpose: The purpose of this study was to assess the influence of blue light-filtering intraocular lenses (IOL) on peripapillary retinal nerve fiber layer (RNFL) thickness measurements by spectral-domain (SD) optical coherence tomography (OCT).

Methods: This prospective study included 50 eyes of 50 patients. Patients were randomly assigned to receive either a blue light-filtering IOL (acrysof IQ (SN60WF) [Alcon]) or a clear IOL (Tecnis (Z9003) [AMO]). The peripapillary RNFL thickness was measured using a Cirrus SD OCT before and 8 weeks after cataract surgery. Perioperative differences in RNFL thickness measurements and signal strengths (SS) were evaluated and compared in both IOL groups.

Results: Thirty-nine eyes of 39 patients were included in the final analysis. There was a significant increase in average RNFL thickness and SS after cataract surgery in both IOL groups. No significant difference in perioperative changes of RNFL measurements was noted between yellow and clear IOL groups. In the multivariable analysis, the factor affecting perioperative differences of RNFL measurements was not IOL type but SS.

Conclusions: Our data suggests that blue-light filtering IOL does not influence RNFL thickness measurements by Cirrus SD-OCT.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.

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