Lysergic Acid Diethyl Amide (LSD-25): XXXVII. Antiserotonin Action of Lysergic Acid Derivatives in Allergy and Neuropsychiatry

Abstract

Although derivatives of d-lysergic acid have been employed in medicine for many years, the knowledge of their unique action on the central nervous system is dependent upon comparatively recent studies. The antiserotonin action of these compounds makes them of special value in the study of allergic mechanisms. Antiserotonin drugs may possibly lead to a more general method of therapy. It is the purpose of this communication to briefly review, and coordinate where possible, the reports of some pertinent investigators looking toward future research.