Comparing dose-volume histogram and radiobiological endpoints for ranking intensity-modulated arc therapy and 3D-radiotherapy treatment plans for locally-advanced pancreatic cancer

Samantha WarrenThe Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK;Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals, Headington, Oxford, UKCorrespondence[email protected]

Mike PartridgeThe Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK;Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals, Headington, Oxford, UK

Emmanouil FokasThe Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK;Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals, Headington, Oxford, UK

Cynthia L. EcclesThe Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK;Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals, Headington, Oxford, UK

Thomas B. BrunnerThe Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK;Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals, Headington, Oxford, UK

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Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

The authors gratefully acknowledge funding from CRUK, MRC, Oxford Cancer Imaging Centre and NIHR Biomedical Research Centre.

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Comparing dose-volume histogram and radiobiological endpoints for ranking intensity-modulated arc therapy and 3D-radiotherapy treatment plans for locally-advanced pancreatic cancer

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