Platelet Values In Amyloidosis

Abstract

Platelet counts have been recorded in respect of 41 amyloidosis patients. Persistently-elevated platelet counts were observable in 22 patients; 19 of them had amyloidosis secondary to rheumatoid arthritis (RA). In patients with amyloidosis secondary to RA, a positive correlation was noted between platelet counts and high Waler-Rose titres. No significant correlations were observable either between platelet counts and haemoglobin or leukocyte values, or between platelet counts and serum protein fractions, nephrotic syndrome or renal insufficiency. As far as is known, the amyloid deposit does not represent any immunological activity. The conclusion is drawn that in amyloidosis, elevated platelet counts are attributable to the underlying disease and its activity.

Dr Olof Selroos, M.D. IV Medicinska kliniken Unionsgatan 38 00170 Helsingfors 17 Finland