![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Normal controls and patients with rheumatoid arthritis (RA) were investigated with respect to quantitative lymphocyte proliferation (LP) after concanavalin-A (conA) activation and to conA-induced suppressor cell activity (conA-SC). Measurements and assessment of RA activity were made at the beginning and end of a 10-day fast. The controls showed depressed (p<0.05) LP at the end of the fast, but no change in conA-SC activity. The RA group showed subnormal (p<0.05) LP and conA-SC (p<0.01) at the beginning of the experiment. After fasting they showed clinical improvement, the LP was not further depressed, and the initially low conA-SC had become normal.