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Scandinavian Journal of Rheumatology Volume 17, 1988 - Issue 4
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Original Article

Phenotypic Changes in Macrophages in Skin Window Exudates

M. L. Wong From the Wellcome Medical Research Institute, University of Otago Medical School, Dunedin, New Zealand
,
J. Highton From the Wellcome Medical Research Institute, University of Otago Medical School, Dunedin, New Zealand
&
D. G. Palmer From the Wellcome Medical Research Institute, University of Otago Medical School, Dunedin, New Zealand
Pages 287-289 | Received 18 Nov 1987, Published online: 12 Jul 2009
 
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Abstract

The number of macrophages (Mph) in the synovial membrane is greatly increased in rheumatoid arthritis (RA) (1) and these cells also predominate in the rheumatoid nodule (2). It is not clear if this results from a normal response to chemotactic factors, or might be due to abnormal behaviour of RA-Mph. The purpose of the present study was to determine whether RA-Mph migrating to skin windows (SW) might show changes in phenotype which differ from normal Mph.

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