Helicobacter pylori Infection Increases the Risk of Peptic Ulcers in Chronic Users of Non-steroidal Anti-inflammatory Drugs

E. K. M. Li Departments of Medicine, Surgery, The Chinese University of, Hong Kong

J. J. Y. Sung Departments of Medicine, Surgery, The Chinese University of, Hong Kong

R. Suen Microbiology, The Chinese University of, Hong Kong

T. K.W. Ling Prince of Wales Hospital, The Chinese University of, Hong Kong

V. K. S. Leung Departments of Medicine, Surgery, The Chinese University of, Hong Kong

E. Hui Departments of Medicine, Surgery, The Chinese University of, Hong Kong

A. F.B. Cheng Prince of Wales Hospital, The Chinese University of, Hong Kong

S. Chung Microbiology, The Chinese University of, Hong Kong

J. Woo Departments of Medicine, Surgery, The Chinese University of, Hong Kong

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Abstract

The objective was to study the gastrointestinal complications in chronic NSAID users with Helicobacter pylori infection. Eighty-two Chinese patients on long-term NSAID or aspirin treatment were studied for the occurrence of H. pylori infection and gastroduodenal mucosal injuries by upper endoscopy. H. pylori infection was confirmed by CLO test, histology and bacteriological cultures. Frequency and severity of symptoms of dyspepsia were also assessed.

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Helicobacter pylori Infection Increases the Risk of Peptic Ulcers in Chronic Users of Non-steroidal Anti-inflammatory Drugs

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Helicobacter pylori Infection Increases the Risk of Peptic Ulcers in Chronic Users of Non-steroidal Anti-inflammatory Drugs

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