X-chromosome genetic variation in São Paulo State (Brazil) population

Abstract

As data on X-chromosomal short tandem repeats (X-STRs) for the Brazilian population are scarse, the aim of this study was to determine the allele frequencies of five X-STRs (DXS6854, DXS7424, DXS101, DXS6808 and DXS7132) in the São Paulo State, Brazil. No deviations from the Hardy–Weinberg equilibrium were observed, with the exception of DXS101. The forensic efficiency parameters demonstrated that DXS101 was the most informative marker. Population comparisons revealed that the X-STR profile sampled in the state of São Paulo was more similar to European and African populations than Asiatic populations reported in this work.

Keywords::

• X-STR
• allele frequency
• São Paulo State
• human identification

Acknowledgements

The authors would like to thank BIOCOD Laboratory (Belo Horizonte, Brazil), PADC/FCF-UNESP (proc. 2006/05-I), CAPES, PIBIC/CNPq, FUNDUNESP (proc. 557/07-DFP) and FAPESP (07/03265-4).

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.