Occurrence of the Codon 24 (A > T) Mutation in the Mauritanian Population

Abstract

Using direct DNA sequencing, we identified the codon 24 (A > T) (HBB: c.72T > A, p.Gly24Gly), mutation in two out of 15 Mauritanian β-thalassemia (β-thal) carriers. Both were of Black origin and had hematological indices compatible with mild β-thal minor. Could this variant be more common than expected in the Black Mauritanian population?

• Codon 24
• Mauritania
• Thalassemia

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.